The first drug which effectively treats coronavirus has been approved by the U.K.’s medicines regulator and is being introduced “as soon as possible” on the NHS. No, it’s not ivermectin. It’s Ronapreve, the same drug, or combination of drugs, used to treat Donald Trump last year. The Times has more.
Ronapreve uses man-made antibodies and prevents the worst symptoms of the virus. The drug is either injected or given through a drip and acts at the lining of the respiratory system where it binds tightly to the virus and prevents it from gaining access to cells.
In June, a large U.K. trial involving nearly 10,000 people found the drug cut the risk of death by about 20% in hospital patients whose bodies were not making antibodies to fight coronavirus.
Donald Trump hailed the treatment as a “cure” and a “blessing from God” after he received an experimental drug cocktail in October last year. It was given emergency authorisation in the US the following month and is thought to cost between £1,000 and £2,000 per person.
Martin Landray, Professor of Medicine and Epidemiology, at Nuffield Department of Population Health, University of Oxford, said: “It combines two antibodies that bind to different places on the coronavirus spike protein, preventing uptake by cells and accelerating clearance of the virus. The rationale for combining two different antibodies is that if a viral variant prevented one drug from binding to the spike protein, the other would still be effective – a ‘belt and braces’ approach.
“This licensing decision is an important step forward. There have been a number of trials in the out-of-hospital setting, each with positive results – reducing viral clearance and reducing the risk of hospitalisation. There have been no major safety concerns.
“The challenge going forward will be in determining which patients should be prioritised for this treatment.”
The Medicines and Healthcare Regulatory Agency (MHRA) said Ronapreve may be used to prevent infection, promote resolution of symptoms of acute COVID-19 infection and reduce the chances of being admitted to hospital.
Worth reading in full.
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I thought Ivermctin was already approved(need to read before i comment)
Fascinating hypocrisy in action.
“the drug cut the risk of death by about [only?] 20% in hospital patients whose bodies were not making antibodies”
“… is thought to cost between £1,000 and £2,000 per person.”
Say no more.
Same with Remdesivir – about £2000 per weekly course – when Ivermectin is a quid.
Can. Nobody. See. The. Problem. With. Our. ‘Health’. Service?
(I know I’m preaching to the wrong people here but still)
Another kerchinnnggg moment for the usual suspects. I’ll take my Ivermectin with a Lemsip chaser, thanks very much
I do not understand why ther is a huge ammount between the lowest and highest estimate. I would have thought it could be calculated more accurately.
What is the point of saying “Worth reading in full” when it is behind a paywall?
Can anyone recommend a reliable (honest and efficient) online source for buying Ivermectin? I remember seeing a recommendation some days / weeks ago, but have not been able to find it.
I did look online, but the only sources were in india and seemed massively overpriced – I’m goint to stick with vit. D and Zinc
A member of a group supporting early treatment, research into how the covid jabs behave in the body, lack of coercion for the jabs etc posted this on using IVM horse paste when unable to get human IVM. He’s based in the US not sure if ingredients are the same as in the UK. This is purely for info!
Ivermectin is known to be very effective as a COVID preventative. If doctors aren’t available to prescribe it, each person can look into and make a decision about forms that are easily available without prescription. When doctors prescribe ivermectin for prophylaxis, the protocol is usually 0.2 milligrams/kilogram body weight taken two times per week. I’ve been taking this myself for nearly a year along with Vitamin D, zinc, etc. I’m comfortable using it and happy with the result and I know many others who are as well.
I’ve attached a flyer explaining how ivermectin is dispensed for horses, for whom the standard dosage is 0.2 milligrams per kilogram body weight. The flyer gives a sense of how it works for smaller animals.
~~~~~~~~~~~~~~~~~~~~~~~~~~
Equine Ivermectin Paste
Available at ag stores (e.g., Tractor Supply) or online, typically around $7.00 to $15.00 for enough to treat a 1,250 pound horse at 0.2 milligrams per pound body weight.
Ingredients (read the label to make sure ivermectin, 1.87% is the only medicine included):
That’s it.
The dosage for horses that’s calibrated on the dispenser is 0.2 milligrams per kilogram of body weight. One tube contains enough for a 1,250 pound horse.
The dispenser plunger is calibrated in 50-pound increment notches. Push the plunger to expel any air from the end of the tube and then count the number of notches adding up to the next higher dose than your horse’s weight if your horse falls in between 50-pound increments. Turn the stop ring to lock it into the appropriate notch, push the plunger, and dispense the paste. It’s about the consistency of grape jelly and holds its shape.
If you need higher doses according to body weight, just multiply the number of notches proportionally. For example, if hypothetically you need a 0.4 mg/kg dose for a 175 pound animal, just set the notches for 350 pounds.
Here’s a helpful video about equine ivermectin paste: https://www.youtube.com/watch?v=QgC1mUe4cNc
Two points:
Not that I’d recommend anyone do this without advice from a veterinarian, of course.
Add Vit B, in case it’s really Beriberi. And get some Quercetin- supposed to be just as good as HCQ.
And use mouthwash.
Works on the same principle as this £2000 solution.
I really wouldn’t trust any overseas sources of ivermectin sold via weird internet sites. There’s a real risk of contamination or even just not getting ivermectin at all.
Frankly, even veterinary medicines in the UK are going to be far far far more reliable than these foreign sources (as they are very tightly regulated and tested). Not that I’m recommending anyone take medicinal products not intended for human use, of course.
India Mart has many sellers but can you trust them?
Trump’s Dr (Zelenko ?) recently advised buying Quercetin which is readily available OTC.
This works with zinc the same way as HCQ & Ivermectin. He recommended taking it in combo with Zinc. I bought some online easy least.
Got mine (and other stuff) from https://www.inhousepharmacy.vu/, been completely reliable, but you need an Amex card to pay.
I got it from this site https://www.genericcures.com/ in India. You pay quite a premium for delivery and it arrived safely after a couple of weeks.
They supplied the normal tracking links and all worked fine. I paid by debit card. Obviously I have no idea if it’s genuine, but it looks kosher
There’s a ‘new’ ivermectin available from Merck called Stromectol (i think) which has been approved by the FDA. I posted about it yesterday. You can get that in quite a few places online, the one i saw was called the Canadian Pharmacy.
After checking many merchants on Indiamart I went with National Medical,Nagpur, Maharashtra.
I paid $11.50 for 50 tablets(12mg) plus $20 shipping. It took about two weeks for them to arrive by post from India. Paid via Wise (used to be TransferWise I think) in sterling – total cost £23.20
Well, I suppose 20% is worth having if it is all you’ve got.
But I’d note that the efficacy of this treatment is for pre-delta variant — this is important, because it is an antibody treatment and as the spike protein mutates it could reduce the drug’s effectiveness.
Also, rather a lot of the data dates from before mass vaccination — we don’t have so much information on how this treatment interacts with the immune system of the vaccinated.
But all that is forgivable, because this is a public health emergency and 20% is worthwhile, even if the supporting data isn’t as good as it should be.
But what’s surprising is that much better levels of supporting data for other drugs that offer a higher performance with lower side effects aren’t good enough for the medical authorities. But then, they’re generic drugs and aren’t going to get the pharma companies £1,000 to £2,000 for every patient.
I’ll add to this.
20% (reduction in cases) was the efficacy seen by the PHE review of vitamin D studies. Even with their efforts to find no effect they got 20% (most studies show a greater effect, but PHE did try very hard). Vitamin D is essentially free and at the doses suggested has no side effects — yet the taking of vitamin D supplements haven’t been pushed as a public duty for all.
The data on vitamin D is overwhelming — if you’re not taking vitamin D supplements to help with covid then you’re a fool (sure, they might not work, but there’s no downside other than a few quid at Wilko).
Ivermectin studies keep on showing at least a 50% efficacy, so long as it is given immediately on onset of symptoms. Sure, the studies are often too small to find significance and often have some problems — but the answer there isn’t to say ‘it doesn’t work’ but to actually do some studies. Now, we do have an ivermectin study in the UK (part of the PRINCIPLE trial), but they’re only giving it several days after onset of symptoms, so don’t expect that trial to show spectacular results. I’ve no idea why there continues to be an inability to fund and design a decent ivermectin trial in the west.
because you don’t make billions pushing a cure that costs nothing.
What do we pay our taxes for? Who do politicians and civil servants serve? And has there been a proper trial of vitamin D yet (Norway and Finland not withstanding)?
There’s the CORONAVIT trial in the UK.
That was supposed to deliver interim results for last winter, but they didn’t.
And that finished two months ago, and which hasn’t reported yet, not even a hint of the data.
I’m pretty sure they’ll mix the winter and summer results together, so that there’s only a minor effect. Anyone with half a brain would analyse the results for winter separately from summer, because of winter vitD deficiency, but then that might show significant results.
Still, mustn’t damn the trial too early — let’s see what they’ve got.
When they eventually get around to reporting them.
From memory their review of vitamin D studies didn’t look at deficiency, which would be why they found such a low effect size. Vitamin D deficiency is common but once you are not deficient the marginal benefit of increased dose against infections seems to be relatively small.
“ this is a public health emergency”
I assume that’s a piss-take?
They have to say that or the emergency authorisation for those “vaccines” is invalid. Belarus may be many things but a public health disaster is not one of them.
Another lab brew concocted in a couple of weeks after a chat round the water cooler.
At least it has been “trialled,” well they had a go in June so no long term, no medium term and oh, no short term results – so that’s alright then. And initial results say it improves outcomes by 20%. How was that measured then?
Obviously the tried and tested Hydroxychloroquine and Ivermectin can’t be used because…..No Profit for Big Pharma. Of course.
So another untried version of paracetamol at €1,000 – £2,000 a pop.
That’s alright then. Tickety Booh.
Sorry, but the first drug to treat covid has been approved in the US in 1955 and it’s called Hydroxychloroquine.
Most effective when taken with zinc 30mg-50mg.
If no access to HCQ quinine sulfate can be bought OTC & there is info available I think Zelenko or Dr Chetty to give dosage.
“This licensing decision is an important step forward.
It certainly is the moment it’s rolled out the emergency authorisation for the clotshots should be rescinded.
Wonder how long it will take them to start using it, not before next year would be my guess as the ‘passports’ aren’t up and running fully yet.
Orange Man Bad. Drug help Orange Man, drug bad.
That’s right. We need a woke, virtue signalling drug endorsed by Sleepy Joe.
Apart from the other drugs that are already used to treat late-stage COVID in hospital, there is budesonide which was approved (rather quietly) for prescribing by GPs in April. The Oxford STOIC trial found that it reduced hospitalisation by 90% when used early https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00160-0/fulltext and the PRINCIPLE trial, which used it on later-stage disease, found a lower benefit of the same order as this new antibody treatment.
The issue I have with this article is that this ‘new treatment’ is for hospitalised patients only, ie the very sick. Clearly it’s offered as it probably doesn’t contravene the EUA hence it’s pathetic 20% benefit.
Ivermectin taken as an early treatment or as a prophylactic is more like 80% but would nullify the EUA.
The take away is still “fuck you, we don’t care about your health”.
Do they now have to stop the ’emergency’ jabs when other treatments are approved?
Exactly, that was my first thought. But ‘the law’ is beside the point at the moment it would seem.
Follow the money and you’ll find the corruption, then you’ll find the truth.
The new drug is £2,000 against Ivermectin at a few pence. Developed by Oxford University who also have 20 members on the SAGE committee as well!
Encouraging a vaccination generating billions in income for the drug companies. Just look at the quarterly earnings for these businesses.
Life really isn’t that hard to understand. Follow the money. For the corruption please download the SAGE committee membership.
Wow 20% reduction in serious outcomes.
Remind me, how effective is ivermectin – or HCQ for that matter.
Surely this will then mean that vaccinations will not be given further emergency use authorisation.
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