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Pfizer Vaccine 98% Effective Against Brazilian Variant

by Toby Young
1 April 2021 10:04 PM

A new study – the largest of its kind – has found that the Pfizer vaccine produces an “off the scale” immune response that is likely to protect against the Brazilian variant of COVID-19. The Telegraph has more.

The biggest study on antibody and cellular immune factors to date suggests people are likely to be protected against the Wuhan, Kent and Brazilian types of coronavirus following two doses of the vaccine.

The research, led by the University of Birmingham and including Public Health England’s Porton Down laboratory, found 98 per cent of people aged 80 or over who had two doses of the Pfizer jab had a strong antibody immune response.

Professor Paul Moss, from the University of Birmingham and leader of the UK Coronavirus Immunology Consortium, told a briefing: “We’ve certainly seen in this paper that the antibody levels are so good, really after the first two weeks, that we are pretty confident that this should be very helpful against the Brazilian variant.”

Worth reading in full.

Tags: Brazilian VariantPfizerVaccines

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26 Comments
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peyrole
peyrole
4 years ago

This is the actual press release from Birmingham
https://www.birmingham.ac.uk/university/colleges/mds/news/2021/04/pfizer-dual-dose.aspx
The study, billed as the largest in the world, was actually of 100 people. And nowhere in the report can you find reference to the headline number of 98%.
The T-cell response was measured at 63% against the original Wuhan virus, with a response up to 14 times less for the Brasillian variant.
So my response is;
The number of participants is too small to be significant, and there is no description of how they have been sampled.
The headline numbers publicised are lies.
Rather than push this out without critical analysis, LDS should have taken the time to read the report and produced a critique, it wouldn’t have taken more than 15 minutes.

53
-1
RickH
RickH
4 years ago
Reply to  peyrole

… and absolute risk reduction – ?

… and 80 or over ??? FFS.

The vaccines are not salvation – they are the thin end of a very big wedge to be shoved up the arses of the gullible.

15
0
LS99
LS99
4 years ago
Reply to  peyrole

It shows the power of words … compare the impact of these two sentences:

In our study of 100 people we found x …
In the largest study of its kind in the world, we found x …..

3
0
Matt Mounsey
Matt Mounsey
4 years ago

You took the bait. Now every stupid story throughout the summer will be about which stupid experimental vaccine is effective against which variant of a virus they haven’t even purified and isolated yet. First rule of public communications? Don’t feed the trolls.

22
-1
helenf
helenf
4 years ago
Reply to  Matt Mounsey

I’ve yet to see a peer reviewed journal article that proves beyond a shadow of doubt how a person contracts covid. That proves transmission, symptomatic or not. All of this hinges on the concept of transmission. If they haven’t isolated the virus, how can they possibly prove transmission from one person to another? So much of science is based on assumption. This is incredibly dangerous when those assumptions are not well founded.

5
0
RickH
RickH
4 years ago
Reply to  helenf

… and how is one key fact explained : that there is only a 17% chance of transmission within enclosed households?

2
0
karenovirus
karenovirus
4 years ago
Reply to  RickH

Added to the ‘fact’ (known since the outset yet ignored until recently) that transmission in the open air is virtually unheard of, hence the ‘fresh air’ tacked onto the latest triptych slogan.

1
0
Shawn
Shawn
4 years ago

It’s yet another positive story for Pfizer. Small, yes, but not insignificant. Taken with the many other real-world studies from around the globe this is all very encouraging and I’m sure we all welcome it. Clearly we all want to see an end to lockdown and, like it or not, the vaccines are a big part of getting that. This vaccine is saving lives

0
-28
Ceriain
Ceriain
4 years ago
Reply to  Shawn

Sarcasm? 77th? You can’t possibly be serious!

14
0
OnceIWasARemainer
OnceIWasARemainer
4 years ago
Reply to  Shawn

Vacciens would save lives if our government wasn’t so stupid as to undermine the rollout by going ahead with magna carta violating passports. I would have taken the jab, but due to recent headlines I shall refuse it. No ID for me, no obedience from me. Vacciens definitely are a way out of covid. Although we can all see clearly from data that the most effective way out of covid is to live NORMALLY until a vaccine is ready, having a vaccine does help turn this mild disease in to an even more insignificant one. Shame this authoritarian disease of a government insists on trying to use the vaccine to implement more social control rather than to unwind the bullshit of the past year. because it isn’t covid we really need a way out of now, it is tyranny which we must eradicate.

11
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RickH
RickH
4 years ago
Reply to  OnceIWasARemainer

“Vacciens definitely are a way out of covid.”

My god! Mystic Meg is posting here! 🙂

(Even the government has backtracked on that)

3
0
LS99
LS99
4 years ago
Reply to  Shawn

April 1 was yesterday Shawn (yes, we geddit, Shawn the Sheep).

2
0
karenovirus
karenovirus
4 years ago
Reply to  Shawn

If these vaccines were being sold to us for cash we should be able to sue under the Sale Of Goods Act, to wit m’lud

“Vaccine-‘any preparation used to confer immunity to a disease by inoculation’ “.

Chambers 20thC Dictionary.

1
0
Cheezilla
Cheezilla
4 years ago

No critique of this load of egregious nonsense?
Pathetic.

7
0
Ceriain
Ceriain
4 years ago
Reply to  Cheezilla

Hi, Liz; looks like we got here at the same time.

TY’s made a fool of himself posting this trash!

6
0
OnceIWasARemainer
OnceIWasARemainer
4 years ago
Reply to  Ceriain

Nought wrong with vaccines so long as they are by choice. The presence of such effective pharmaceutical interventions (in contrast to NPIs which never work) should make the bedwetters calm down. Except that the bedwetters have been so hyped over the past year of BBC fearmongering that they no longer have the sense to see that whilst vaccinations might be nice options to have, society could have functioend normally throughout this past year before they were ready, and with them available there is no excuse to go back to anything other than full normality. The success of the vaccines themselves among those who want them is yet more proof that there is no need for such fascist lunacy as lockdowns or vaccine passports.

5
-2
peyrole
peyrole
4 years ago
Reply to  OnceIWasARemainer

It would be true if there were really any evidence that they work, ie stop transmission, create immunity. If all they do is reduce symptoms, then Ivermectin has at least as good a track record at a fraction of the price.
Israel shows increased all mortality deaths since the vaccine roll-out, Chile is back in lockdown after a vaccine roll-out at least as quick as UK.
The motives for the ‘fascist lunacy’ are increasingly seen as divorced from the virus.

12
0
RickH
RickH
4 years ago
Reply to  peyrole

The safety record of Ivermectin is established. That of the vaccines isn’t.

The effectiveness of Ivermectin is properly known. That of the vaccines isn’t.

4
0
BurlingtonBertie
BurlingtonBertie
4 years ago
Reply to  OnceIWasARemainer

Hand washing as part of basic infection control does work, but I agree with everything you said about the other NPIs for Covid. Norovirus normally goes through hospitals & nursing homes in the winter, no outbreaks reported with the increased amount of hand hygiene. Only positive thing about the whole fiasco!

3
0
RickH
RickH
4 years ago
Reply to  BurlingtonBertie

Yes – some way back, early in this shit-show, I was talking with a specialist nurse who remarked that the hand-washing campaign’s main benefit had been to reduce other key infections such as norovirus.

2
0
RickH
RickH
4 years ago
Reply to  OnceIWasARemainer

“Nought wrong with vaccines so long as they are by choice.”

… and are properly tested. Which these aren’t.

4
0
nickersan
nickersan
4 years ago

I’ve recently read Ben Goldacre’s Bad Pharma – it’s amazing how many of the tricks (sighted in the book) used to make the results of clinical trails appear better than they are keep popping up in the various vaccine trials.

Yes there’s the use of relative efficacy rather than absolute, but I noticed another one here:

This trial seems to be using a surrogate endpoint – the presence of antibodies, rather than a difference of confirmed ‘cases’ between the trial and placebo groups.

4
0
RickH
RickH
4 years ago
Reply to  nickersan

Yes – always look for absolute risk reduction figures (and question why if they are absent).

3
0
LS99
LS99
4 years ago

News that the Pfizer jab produces an “off the scale” immune response should in any sane society cause serious concern rather than be something to boast about, given the unexplained and rapid rise in autoimmune conditions in the UK population.

https://www.immunology.org/news/report-reveals-the-rising-rates-autoimmune-conditions

6
0
Ruth Sharpe
Ruth Sharpe
4 years ago

Is that the one, where they have also discovered that giving the 2nd dose of Pfizer to people who have already had the so-called ‘wild virus’, actually reduces their T-cell count & makes them more susceptible to the virus?

Hope I’ve got that right!

1
0
Jane G
Jane G
4 years ago

I’m just waiting to see when it will turn out to be a cure for cancer, premature baldness and piles. (Not that I’ve got any of these, please God, but you get my drift)

1
0

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