A few days ago, I came across Dr. Viki Male, qualified with a science PhD in pathology rather than a medical degree, who lectures in reproductive immunology at Imperial College London. Dr. Male, cocooned in a white coat to provide the necessary medical gravitas, was the star of an NHS video promoting COVID-19 ‘vaccinations’ (more properly experimental gene-based therapies) to pregnant mothers.
The autumn booster is strongly recommended for pregnant women, who are at higher risk of getting seriously ill with Covid
— Department of Health and Social Care (@DHSCgovuk) November 3, 2022
Immunologist Dr @VikiLovesFACS from @ImperialCollege explains why it's so important to get vaccinated.
More info: https://t.co/TgSJoMVMMz pic.twitter.com/Rb21eQE44Z
Now it is a fact that pregnant mothers were deliberately excluded from the clinical trials of all the COVID-19 vaccines. It follows that we have no data on the safety of these experimental medications from properly designed trials in which outcomes for treated and untreated pregnant women are compared. Neither do we have any long-term data on the effects of these experimental medical treatments on mothers and their unborn children. Without this evidence to support her case, Dr. Male’s strident promotion of the COVID-19 vaccines to pregnant mothers could only have been based on a belief that they do no harm, rather than on any scientific proof.
However, Dr. Male did seem very sure of herself, despite her exposed position. I therefore determined to look at the quality of the data that she used to shore up her belief system. Like Dr. Male I am qualified with a Ph.D. in biology, and throughout my career I have been involved in the peer review process, assessing the scientific quality of papers to determine whether they meet the standards required for publication. Dr. Male, in response to criticism of the NHS video on her Twitter feed, gave great prominence to a recently published paper from a group led by Professor Sarah Stock at Edinburgh University entitled “Early pregnancy outcomes following COVID-19 vaccination and SARS-CoV-2 infection: a national population-based matched cohort study“. I therefore determined to review this paper myself, and assess whether the analyses that it presented supported the conclusions that had been drawn, and whether the manuscript was worthy of publication.
My verdict is that if I were a reviewer of this paper, I would unequivocally reject it on the grounds that the data on which it is based are unsound, that it fails to analyse the crucial interaction between vaccination status and SARS-CoV-2 infection, and that the conclusions drawn are not supported by the results presented. Indeed, the only significant result to emerge from the study is that there were higher odds of early miscarriage among women receiving the AstraZeneca vaccine when compared to historical controls (17% higher: adjusted odds ratio 1.17; 95% CI:1.03-1.34). I outline the full reasons for my verdict below.
The paper retrospectively compares matched cohorts of vaccinated and unvaccinated women to assess whether they differed in the frequency of either pregnancy loss in the first 20 weeks or ectopic pregnancy. Comparisons in the frequency of these deleterious outcomes were also made between cohorts of pregnant women who did, or did not, test positive for the SARS-CoV-2 virus. In order to assess the overall quality of the research, it is first important to determine the quality of the data on which it is based.
The research is critically dependent on unambiguous classification of individuals into the categories vaccinated or unvaccinated, infected or uninfected. The authors concede that there may be significant problems here:
We had to rely on imputed gestation at end of pregnancy for a high proportion of pregnancies ending in early loss, which may have led to misclassification of vaccination or infection status.
Specifically, if the total length of the pregnancy was not known it was assumed to be uniformly 10 weeks for miscarriages or eight weeks for ectopic pregnancies. Making these assumptions could lead to misclassification of the vaccination or infection status of individuals.
Secondly, the research depends on accurate recording of rates of miscarriage. Again, there are problems with these data:
We could not include early miscarriages where the woman did not seek healthcare advice.
Finally, the distinctive point of this study, that it involves matched cohorts that do not differ for confounding factors, is thrown into doubt by the admission that three key factors, well known to influence pregnancy outcomes, were not matched:
We were not able to adjust for body mass index (BMI) or smoking; or include diabetes in clinical vulnerability scores.
The next area for scrutiny is how these compromised datasets were analysed. Two features of the treatment of the data are concerning. Firstly, before comparison of the vaccinated and unvaccinated cohort was performed, all women with a positive SARS-CoV-2 test during the study period were excluded. Secondly, before pregnant women with and without a SARS-CoV-2 positive test were compared, all vaccinated individuals were excluded.
The effect of these exclusions is that the interaction between vaccination status and presence or absence of SARS-CoV-2 on pregnancy outcomes is ignored. This is a serious omission because vaccination takes place in the presence of SARS-CoV-2 in the community (the whole reason that vaccination is being promoted). Therefore, we need to study the effect of vaccination in the presence of SARS-CoV-2 infections, not in their complete absence. A major reason for doing this is that recent data suggest not only that vaccination does not prevent infection by SARS-CoV-2, but that vaccine recipients may have a higher chance than unvaccinated of testing positive for SARS-CoV-2 and suffering from COVID-19. If we ignore this effect by excluding individuals who are SARS-CoV-2 positive, we are not obtaining a true comparison of the real-world effects of vaccination on pregnancy outcomes.
Notwithstanding these serious flaws in the analysis, we can now look at the results that were obtained and the conclusions that were drawn from them by the authors. Looking across all the data presented, no significant effect of SARS-CoV-2 infection on early pregnancy outcomes was detected in this study. The only significant result to arise from the study was that there were higher odds of early miscarriage among women receiving the AstraZeneca vaccine when compared to historical controls (17% higher: aOR 1.17; 95% CI1.03-1.34). Therefore, the conclusion that should be drawn from this study is that there is no evidence that SARS-CoV-2 infection poses a risk to early pregnancy outcomes, but that vaccination with the AstraZeneca vaccine increases the risk of early miscarriage.
Curiously, this is the inverse of what the authors actually concluded in their manuscript:
Overall, our analyses found no evidence of an increased risk for miscarriage or ectopic pregnancy after COVID-19 vaccination, supporting current recommendations that vaccination remains the safest way for pregnant women to protect themselves and their babies from COVID-19.
So, Dr. Male, this is the standard of scientific evidence upon which you base your advocacy of the COVID-19 vaccines for pregnant women. The only significant result that comes from the study suggests that at least one of the vaccines increases the risk of early miscarriage. I believe the only honourable thing for you to do is forthwith to withdraw from further promotions of the COVID-19 vaccines for pregnant women. There is more than your scientific reputation at stake. There is the future happiness of all pregnant women who place their trust in you because you have been put forward as a scientist and individual of integrity.
Dr. Richard Ennos is a retired Professor of Evolutionary Biology at Edinburgh University.
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Excellent analysis, thank you for this. $cience. I can guess who paid for this ‘study’. Peer review has long been a bit of a joke (been involved in such reviews myself). No time, no access to data, unpaid, ‘you approve mine I will approve yours’ etc. Just a mantra and myth within the cult of $cience.
“My verdict is that if I were a reviewer of this paper, I would unequivocally reject it on the grounds that the data on which it is based are unsound, that it fails to analyse the crucial interaction between vaccination status and SARS-CoV-2 infection, and that the conclusions drawn are not supported by the results presented”
‘Turles all the Way Down’, also provides very similar examples of outrageous data fraud, lack of relevant control groups, lack of dependent/independent variable analysis, attributions that are from studies whose data do not support the stated pre-ordained conclusions, or studies that are so old as to be useless in the current context of the mRNA stabs.
Excellent article, thank you, Doctor.
I do feel rather like I felt on 31 December 1999, when the world was celebrating our entry into “The New Millennium”:
I know it’s not the start of the New Millennium. You know it’s not the start of the New Millennium. But who are we?!
This time, however, the stakes are somewhat higher…
I’d love to see her go head to head in a debate with Dr Thorp. He’d wipe the floor with her due to his extensive experience and research. These unethical liabilities to the public should be struck off/sacked. They’re a menace to society, but I guess the terms “misinformation/disinformation” only apply when you’re challenging the narrative.
Great article; thanks.
Thank you for your article . It so upsetting to read because as I regard this as medical malpractice and it is causing at least serious heart ache. I know young women who have had miscarriages and are finding it difficult to get pregnant. I know that correlation isn’t causation necessarily for them but it makes one wonder? Is the vaccine the reason for their loss?
They are in denial of course themselves because if it is, it will be more difficult to bear.
Yet again I am filled with anger reading another abject failure to adhere to the scientific method.
Remember “primum non nocere”?
Remember thalidomide?
I despair at what a once honourable profession has become.
Indeed. I give the example of Frances Oldham Kelsey to many people and all I get back is either complete ignorance, or,
“Oh, that couldn’t happen these days.”
The horrible symptoms of Thalidomide in babies were obvious for all to see. And it still took years to ban it. Just think about the symptoms of myocarditis…
And Oscar Semmelweis. Denounced and forgotten, despite his critics accepting his observations and his message – and then not crediting him.
And to think that the FDA and the MHRA used to be filled with people like Dr Kelsey
https://naomiwolf.substack.com/p/vote-like-a-woman/comments
https://www.conservativewoman.co.uk/effects-on-mother-and-child-that-bear-out-mike-yeadons-warnings/
I am sure Matt Hancock’s £400k fee for talking self-exculpatory voodoo BS science to an audience of idiots via I’m a Celebrity will be offered to Iatro-geno-cide aware groups for the support of gene therapy victims and their families.
Or will he simply trouser it and continue his delusional existence?
Dear Dr Viki Male, Immunologist at the bought and paid for Imperial College, your disgusting Twitter video encouraging the most vulnerable people in society to ‘come forward’ to be poisoned and put themselves and their babies at risk from an entirely and self-evidently unnecessary injection, will ultimately be evidence used against you in your war crimes trial.
You are either so thick that you’ve believed the lies of your superiors, so evil that you enjoy the thought of babies dying, or so greedy that you don’t care either way.
Whichever it is, you and your superiors will pay heavily for this crime and your lies will come back to haunt you.
Hopefully all the haunting will start with her being sued personally for the harm she has caused
Ignorance and obeying orders was no excuse I’m afraid she will have to pay for her crimes.
Great analysis.
I’d add that there seems to be a complex interaction between the post vaccine immune system and the impact of Covid infection. It would be useful if there was much more research in this area.
Perhaps Drakeford can help?
Made me chuckle!
Male’s opinion is annihilated by Thorpe.
https://www.preprints.org/manuscript/202209.0430/v1
The sheer depravity of Male’s crime is accentuated when taking in to account the huge volume of evidence which destroys her position.
How the hell does she sleep at night after promoting these maim and kill injections?
I’ve taken issue with this appalling shill on Twitter. She’s a dreadful excuse for a human being. Incredibly thick, but an absolute believer in her own credentials. Smug and vile.
Hopefully she is taking so many of these jabs that she will render herself infertile and the world will be spared the continuation of her genes.