A study from Stanford University, published in Cell, has found that vaccine mRNA and spike protein persist in lymph nodes for up to two months following the second vaccine dose. This is in contrast to what happens following infection, where spike protein was found only rarely.
In contrast to disrupted germinal centres in lymph nodes during infection, mRNA vaccination stimulates robust germinal centres containing vaccine mRNA and spike antigen up to eight weeks postvaccination in some cases…
The observed extended presence of vaccine mRNA and spike protein in vaccinee lymph node germinal centres for up to two months after vaccination was in contrast to rare foci of viral spike protein in COVID-19 patient lymph nodes… COVID-19 patient lymph nodes showed lower quantities of spike antigen.
The researchers also found the concentration of spike protein in the blood following vaccination was similar to that during infection.
At least some portion of spike antigen generated after administration of BNT162b2 becomes distributed into the blood. We detected spike antigen in 96% of vaccinees in plasma collected one to two days after the prime injection, with antigen levels reaching as high as 174 pg/mL. The range of spike antigen concentrations in the blood of vaccinees at this early time point largely overlaps with the range of spike antigen concentrations reported in plasma in a study of acute infection, although a small number of infected individuals had higher concentrations in the ng/mL range. At later time points after vaccination, the concentrations of spike antigen in blood quickly decrease although spike is still detectable in plasma in 63% of vaccinees one week after the first dose.
The researchers found evidence of ‘original antigenic sin’ from the vaccines, where a person vaccinated and then infected with a variant develops a weaker antibody response to that variant than an unvaccinated person infected with the variant. They describe it as a “strong imprinting effect of prior vaccination”.
We find that prior vaccination with Wuhan-Hu-1-like antigens followed by infection with Alpha or Delta variants gives rise to plasma antibody responses with apparent Wuhan-Hu-1-specific imprinting manifesting as relatively decreased responses to the variant virus epitopes, compared with unvaccinated patients infected with those variant viruses…
The extent to which vaccine boosting or infection with different variants will effectively elicit antibody responses to new epitopes or rather increase responses to the epitopes of antigens encountered previously, as in the ‘original antigenic sin’ phenomenon described for influenza virus infection and vaccination, will be an important topic of ongoing study.
The researchers confirmed the fast decline of antibodies following vaccination, finding a 20-fold drop after nine months.
Our data demonstrate that vaccinee plasma and saliva spike and receptor-binding domain-specific IgG concentrations decrease from their peak values by approximately 20-fold by nine months after primary vaccination but quickly exceed prior peak concentrations in seven to eight days after boosting with a third vaccine dose.
The study also confirms that vaccination doesn’t generate IgA antibodies (found especially in the respiratory and digestive tracts and mounting a first defence against infection) or IgM antibodies (found especially in the blood and lymph fluid), but only IgG antibodies (found in the blood). This has been proposed as a reason that vaccination is so poor at preventing infection and transmission.
Surprisingly, perhaps, the researchers found that vaccination (whether mRNA, adenoviral or inactivated virus) stimulated a broader antibody (IgG) response than infection, leading them to predict that “antibodies derived from infection may provide somewhat decreased protection against virus variants compared with comparable concentrations of antibodies stimulated by vaccination”.
However, the post-infection IgG antibody response improved over several weeks.
Over time, infected patient plasma samples showed improvement in variant receptor-binding domain binding relative to Wuhan-Hu-1 receptor-binding domain, suggesting evolution of the antibody response through at least seven weeks post-onset of symptoms.
In addition, the apparent breadth-benefit of vaccination over infection disappeared when “whole spike antigens” were tested rather than just the receptor-binding domain targeted by the vaccine, suggesting the benefit may be an artefact of the study design not found in a real encounter with the virus.
Notably, the increased breadth of vaccinee IgG compared with COVID-19 patient IgG binding to viral variant antigens was greatest for receptor-binding domain, the main target of neutralising antibodies, and was decreased or not detected when whole spike antigens were tested.
Other limitations mentioned include not looking at “antibodies binding to the spike N-terminal domain” or other antibodies: “Our data do not reflect potentially functional antibodies binding to the spike N-terminal domain, or antibodies that may have other activities in vivo.”
The study also didn’t look at T cell responses, among other things:
Further mechanistic investigations into the differences in antibody breadth elicited by vaccination and infection are needed to define the roles of T cell help, antibody affinity maturation, germinal centre function, and innate immune responses to vaccine components, as well as the cellular and subcellular distribution of vaccine RNA and expressed antigen in lymphoid tissues.
The high concentration in the blood of spike protein following vaccination and its persistence along with vaccine mRNA in lymph nodes for months, in contrast to the situation post-infection where such persistence is rare, will fuel concerns about the safety of these Covid vaccines. It has been argued that the spike protein is itself pathogenic, not inert, and that the free spike proteins generated by the vaccines have greater capacity to bind to more types of cells than the virus particles themselves, and that this may be what lies behind many of the serious adverse events reported to regulatory bodies and identified in case reports. This warrants further investigation.
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We are seeing the slow de-stigmatisation of terms which, the mere mention of in public, would have ended careers this time last year. First to fall were herd immunity then natural immunity. Now we have the acceptance of original antigenic sin. Maybe Ivermectin will fall next!
The next challenge is to be very precise in identifying which dark, monovalent forces have spent the past 2 years trolling the internet and social media to make these phrases so unacceptable. We all know these things don’t happen by accident. Who would have most to gain by censoring debate in this way?
Billy Goates
Ivermectin Has Fallen!
Gerard Butler returns as Mike Banning. After watching his wife die cos clown doctors wouldnt give her Ivermectin, Banning goes deep underground and enlists the help of Malone, McCullough, Rogan and Brand to bring down the big state once and for all. In the shady world of gutter science they uncover unbelievable papers and documents known in the underworld as evidence. Can they prove that the science isnt settled?
Tickets available now for a box of horse dewormer.
“The researchers found evidence of ‘original antigenic sin’ from the vaccines, where a person vaccinated and then infected with a variant develops a weaker antibody response to that variant than an unvaccinated person infected with the variant. “
“Attempts to develop an RSV vaccine began in the 1960s with an unsuccessful inactivated vaccine developed by exposing the RSV virus to formalin (formalin-inactivated RSV (FI-RSV)).[1] Unfortunately, this vaccine induced a phenomenon that came to be known as vaccine-associated enhanced respiratory disease (VAERD), in which children who had not previously been exposed to RSV and were subsequently vaccinated would develop a severe form of RSV disease if exposed to the virus itself, including fever, wheezing, and bronchopneumonia.[1] Some eighty percent of such children (vs. 5% of virus-exposed controls) were hospitalized, and two children died of lethal lung inflammatory response during the first natural RSV infection after vaccination of RSV-naive infants.[1] This disaster hindered vaccine development for many years to come”
I think I’m still at the ‘wait and see’ stage with regard to getting vaccinated!
Hard to see why you haven’t yet made up your mind.
me waiting to make up my mind
Funny enough, though for me, it pushes the pro-vax agenda.
At least you weren’t one of those who gained too much weight during the lockdowns.
There’s a very nice explanation of what the spike protein is, where it goes and how long it hangs around on the “Science with Dr Doug” podcast (on Spotify).
https://anchor.fm/ScienceWithDrDoug
And see also this from Steve Kirsch
Things you should know about the new Pfizer documents (substack.com)
Here are the some of the issues we will cover in this review. More to come as we learn more:
AND see also this
Whilst you’ve been distracted by Russia-Ukraine, the UK Government quietly published data confirming the Triple Vaccinated are just weeks away from developing Acquired Immunodeficiency Syndrome – The Expose (dailyexpose.uk)
The latest official figures from the UK Health Security Agency show that triple vaccinated people aged 30-70 have now lost at least 70% of their immune system capability compared to the natural immune system of unvaccinated people.
Their immune systems are deteriorating between 10 and 30% per week on average, with the deterioration much larger and quicker among the younger age groups.
If this continues at the current rate then all triple vaccinated 18 to 39-year-olds will have 100% immune system degradation by the middle of April 2022, with all other triple vaccinated age-groups following suit not long after.
In other words, official UK Government data strongly suggests the triple vaccinated population are rapidly developing acquired immunodeficiency syndrome.
While the shot-up x3 are destroying their immune systems, they continue to lord it over us. I get emailed every week requests to renew membership at The Met, Pierpoint Morgan etc. museums, but these once great, now ridiculous institutions bar my entry because I have taken the rational decision to protect my health.
Will they be the authors of their own demise?
Dr Mobeen covered part of this study yesterday in this excellent video
Spike Protein Gets In The Blood of Vaccinated Individuals (Firm Data From A Stanford Study)
https://www.youtube.com/watch?v=-Y7dTMzn9B8
He’s intending covering some other aspects of the study in later videos
Nice to see this research being done. Shame that it was done after vaccinating the world, not before.
There are two problems with the longer term persistence of spike protein:
I’d note that in the case of immune tolerance, it might be that 2 months ‘isn’t enough’ — but we’re giving repeated vaccinations at 3 month intervals, which would lead to a consistently high level of spike and spike production in the lymphatic system (according to the OP’s paper) over many months, which is certainly getting into ‘worry’ territory.
The potential for OAS is just the icing on the cake.
I agree with all of this. Nothing more to add. The mass and repeated administration of these biological agents is nothing short of catastrophic folly.
I’m going to be looking closely at companies working on development of drugs tackling misfolded proteins….seems like it could be a good investment.
do you mean as a kind of antidote to the damage done by the jabs?
Dr Kat Lindley, one of the medics who set up the World Council for Health, has developed a bioweapon injection detox plan with which she has had a lot if success.
Home | Katlindleydo
Indeed. I can remember as far back as when injections were tested for safety before being shot into the arms (and elsewhere) of populations.
Of course, if you’re a shabby pharma company, you’d rather be able to jab first, make your profits and relax, since those nice government folk gave you a ‘stay out of jail’ card should there prove to be any unfortunate outcomes from receipt of your elixir.
A ‘get out of jail free’ card indeed, which will become void if it is found that they falsified efficacy data and/or adverse reaction data. There’s good reason pfizer tried to bury their papers for 75 years.
Yet why did the FDA fight so hard for the same?
Fauci and others of his ilk
Clotting and heart-related problems caused by the fake vaccines dwarf any claimed to be caused by covid.
yes,
not exactly the surprise of the century, wasn’t mike yeadon saying this a yr ago?
The Salk Institute published a paper around March 21 which pointed towards this pathogenicity of the spike. They were quickly admonished to update their paper with a statement to say it was OK, the spike from vaccination was different from infection. Or something to that effect.
Who did the admonishing?
Billy Goates’ gruff media pals and the WHO, CDC, NIAID etc etc
An acquaintance told me today her four month old grandaughter is in hospital due to covid, mum’s vaccinated. I wonder if the vaccine can supress babies immune systems making them more vulnerable?
I have read that while the young are at very low risk from the infection compared to the elderly, this is not the case for the very young whose immune systems are particularly immature. It may also be the case that the health of the mother – inadequate D3 etc – fails to set the baby up properly.
https://www.youtube.com/watch?v=-Y7dTMzn9B8&t=1212s
Spike Protein Gets In The Blood of Vaccinated Individuals (Firm Data From A Stanford Study)
I am so, so glad I never succumbed to the pressure and took the juice. Just coming out of a covid infection right now and I can honestly say I have had worse colds. And at least I have natural immunity from now on.
May I ask whether anyone who is still a vaccine holdout has managed to obtain a ‘Covid Recovered Certificate’ as many EU countries will now accept these at entry within 6 months of a positive test.
I know that they are automatically issued in Switzerland and EU countries, but so far over here they are hidden with the British Brexit Unicorns and Boris won’t give them either.
Anyone got one yet?
an option is if you have a positive test there is a nhs online form that asks for that code given at the time of the negative. Of course this is all control and I had to test to go to work ! And you have to download the nhs app… more control
How obvious!
Who could have guessed? Still they don’t wake up!
Still radio adverts trying to tell me that vaccination is the ‘best choice’ for 12-15 year olds so roll up roll up for their second dose
Another nice find….
The Hubris of Modern Medicine Caused Billions to Be Injected With “Hidden Genes” in the mRNA Sequences in COVID-19 Vaccines. It’s Time We Tell Them We Know.
https://popularrationalism.substack.com/p/the-hubris-of-modern-medicine-caused
COMMENT: A WORLD GOVERNMENT UNDER THE AUSPICES OF THE WHO AND THE UN PROMISES US? – Platforma39 (domengorenseklaw.com)
and they will do precisely the same the next pandemic around and there won’t be a thing we can do about it when our sovereignty has been passed to the WHO.
Test.