Well, what do you know? It feels like yesterday, and we have already written loads about Comirnaty, the Pfizer/BioNTech Covid vaccine, and the properties of its two lipid nanoparticles (LNP) and modified messenger RNA. So, have our readers, who have commented in their droves, Just look at this diagram drawn by Picasso Heneghan:
This is a list of firm points and 15 questions we have established so far on the pharmacokinetics (how the body interacts with a drug) of Cominarty:
The lipid ‘excipients’ ALC-0315 and ALC-0159 were new. Regulators note the limited experience with these compounds.
1. Whose job is it to close the gap in evidence and ensure patient safety when new experimental compounds are included in vaccines?
Experience of their use in humans was limited. They act as the carriers; the RNA is a different story. The metabolites were found everywhere in the rats’ organs (liver, spleen, ovaries and so on).
The significance of their widespread distribution is unclear for humans, but the concentrations were very high in the liver and ovaries and almost certainly toxic.
2. Does this hold true for humans, too?
3. What is the possible toxicity of LNPs in humans, especially after repeated exposures?
Vaccine particles (antigens, adjuvants and excipients) in other vaccines are not usually found in many internal organs; they are usually concentrated around the injection site. We are unclear about the half-life, although the EMA seems to think it is long.
4. Is there a dose-response?
5. What is the half-life of mmRNA in the elimination phase in different organs?
6. What happens to the mmRNA in humans in different organs?
One or more of their ingredients are considered carcinogenic.
7. Why were no carcinogenic studies carried out in animal models prior to provisional licensing?
8. Why were no genotoxicity studies carried out in animal models prior to provisional licensing?
Nanoparticles are vastly different, and some are toxic, which is concerning. Our understanding of their behaviour in complex biological systems is extremely limited.
9. Where are the post-marketing studies following up on the cancer risk?
The Japanese regulator considers Cominarty as a “powerful drug”. Cominarty is a formulation consisting of tozinameran encapsulated in LNP.
10. Should mmRNA vaccines be classified as a drug?
11. Why is a modified messenger RNA abbreviated to mRNA, which we are taught stands for messenger?
The Japanese regulator reports Pfizer’s explanation that the pharmacokinetics of mmRNA formulation encapsulated in LNP is dependent not on the encapsulated mmRNA but on the LNP.
12. Is the LNP inert as Pfizer claims it is?
The MHRA enabler (formerly a regulator) does not know anything about the metabolism of the nanoparticles or the mmRNA, nor does it hold vigilance data for the Covid vaccine harms, and it knows nothing about the rate of underreporting of harms.
13. Whose job is it to ensure patient safety if the regulator/enabler is wilfully ignorant of the evidence of harm at the approval stage of novel vaccines?
There are no published studies of Cominarty in pregnant women. All the regulators report in the package insert that: “No data are available yet regarding use during pregnancy” (EMA and MHRA) and “The available data on COMIRNATY administered to pregnant women are insufficient to inform vaccine-associated risks in pregnancy” (US FDA).
14. Why has the only randomised controlled trial on pregnant women not been published?
15. Why does the messaging to the public differ from what is reported in the package inserts for pregnancy?
For now, we are leaving the pharmacokinetics behind (we’ll likely return) and moving on to the heavy lifting of determining the effects of Cominarty.
This post was not written by impersonators and is not commercial in confidence. It is not carcinogenic and will not self-disrupt or autodelete. We are not on the payroll of any pharmaceutical company, and given the content of our posts, we have been notified that HMG will award us the order of the boot.
Dr. Carl Heneghan is the Oxford Professor of Evidence Based Medicine and Dr. Tom Jefferson is an epidemiologist based in Rome who works with Professor Heneghan on the Cochrane Collaboration. This article was first published on their Substack, Trust The Evidence, which you can subscribe to here.
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What I’ve learnt about them is that they were well worth avoiding, especially w.r.t. the way they were marketed.
Remember
As many of you know, four weeks from today, in the King’s Bench Division of the High Court of England, shall be heard:
The King on the application of Mark Steyn
vs
The Office of Communications
What is it
Britain and indeed the world owe Doctors Heneghan and Jefferson a huge debt for putting themselves front and centre in this battle with the anti human forces behind big pharma. I remember the early days when these good men were the very essence of politeness and restraint, now, quite rightly the gloves are off.
God bless them both.
Even though it has been more than four years since the start of “covid”, and fair while since “covid” was “over”, I cannot fathom the enormity of what was done, and the lack of interest most people show in it to this day. Articles like this really bring this home to me. Monstrous.
With you on that tof.
It’s almost like every morning I wake up and wonder if it was all a bad dream. I will never get my head round it.
That is pretty much where I am. I lay in bed this morning and couldn’t help but think “what have the youngsters got in front of them?”
It looks to me as if Orwell’s ‘1984’ is a real possibility within a barbaric muslim nightmare. I don’t see a future of hope I see a future of violence, depression and drudgery. Bleak. Very bleak.
It can seem like that
I just try to take care of me and mine and don’t give the bastards the satisfaction
I will never forget and never forgive. I want the guilty men and women treated the same way the Nazis were at Nuremberg.
A nightmare, like you and Hux, just cannot get my head around what happened and how it happened.
I though we Brits had something about us, the Bulldog spirit is dead and gone.
I thought we would be what Sweden were, and I thought Sweden would act like we did!
Something is seriously broken in the British psyche, it is a dead psyche it is no more!
I’d read into disaster planning and dystopian end times, but just never saw it coming. When the CMO’s of the British nations announced on 19th March 2020 the reduction from HCID I honestly that was it, we would be scaling back the rhetoric and the scaremongering, and calling out Neil Ferguson as the charlatan he clearly was – how very wrong I was!
I even naively believed that the NHS existed to save us!
I regret nothing I did in resisting the madness, but friendships have been lost!
I’m yet to regret not getting the vax that’s not a vax, and still strongly believe I made the right call, and will be vindicated.
Ditto !
https://youtu.be/BnTjmSv8VNo?si=88jzHda1vOoA1W5C
Paul Weston on YouTube with the perfect accompaniment to this article. Lots of Abduls on the take – literally.
A sincere thank you for all the hard work you have done over the last 3-4 years re the “pandemic” etc and for your work prior to that in trying to extol the benefits, nay necessity, of evidence based medicine.
I look forward to seeing Carl appearing on the BBC soon – no doubt shortly after the Guardian has invited him to write a series of articles criticising lockdowns, masks, school closures, social distancing, modified RNA and their untested lipid nanoparticles, the dangers of mass vaccination etc. etc.
That said, remember he’s up against luminaries such as the writer of this tripe –
https://www.theguardian.com/world/article/2024/may/11/astrazeneca-covid-vaccine-jab-coronavirus-saved-lives-humanitarian-crises
According to the author of the linked Guardian article the AZ “vaccine” saved 6.3 million lives in 2021 alone. Later in the article we get this…
“We only know those who were harmed by it but cannot pinpoint those who benefited.
Again, this makes it trickier to pinpoint a vaccine’s success and assure people of its efficacy.”
But they were able to pinpoint efficacy to 6.3 million lives. This Robin Mickie is quite frankly a dangerous liar.