IgG4 refers to a special rare subclass of antibodies instructing our immune system to ignore a pathogen rather than fight it. We learned that repeat Covid vaccinations cause immune tolerance in boosted people, which makes them less able to fend off repeat infections.
While IgG4 antibodies may naturally appear in allergies due to repeat immune stimulations with allergens, they are inappropriate for replicating pathogens such as SARS-CoV-2.
What causes such dysfunctional antibodies to appear in Covid-boosted people? Was the IgG4 class switch mechanistically caused by repeat injections or by the nature of mRNA technology? In August of 2023, I suggested that the culprit may be continued production of spike protein encoded by the mRNA Covid vaccines.
An interesting new preprint study confirms that suggestion. It compared the immune outcomes of three injections with mRNA vaccines against the effects of three injections of a protein-based vaccine called Novavax.
Scientists discovered that, despite all groups of patients receiving three injections, the IgG4 class switch happened only in the mRNA group.
Compared with recipients of prior mRNA vaccine, anti-S IgG3 levels were markedly higher (>10-fold) after three or four homologous doses of NVXCoV2373. By contrast, much higher anti-S IgG4 levels (>75-fold) were observed following repeated mRNA vaccination, but not after three or four homologous doses of NVX-CoV2373 (Fig. 1A).
The study compared three groups of patients:
- Those who received three doses of the Pfizer mRNA vaccine
- Those who received three doses of the Moderna mRNA vaccine
- Those who received three doses of Novavax Covid vaccine (no mRNA)
The Novavax vaccine has no mRNA and is an injection of “spike protein”, adjuvanted with a certain substance called Matrix-M. The job of the adjuvant is to make the vaccinated person feel sick and trigger an immune reaction to the protein contained in the vaccine shot. Many other vaccines given to people in the past were of this type.
You can see that, compared to Novavax, mRNA vaccines result in IgG4 levels that are thousands of times greater (the scales below are logarithmic):
What can we conclude from this?
The Novavax group, as well as the mRNA groups, were thrice-vaccinated.
And yet, only the mRNA groups had sky-high levels of IgG4 antibodies.
Study authors explain:
Increased concentrations of IgG4 have been associated with immunosuppression and poor clinical outcomes of COVID-19, and while generally regarded as anti-inflammatory, may contribute to some auto-immune disorders and inflammatory IgG4-related diseases. Following repeated mRNA vaccination, IgG4 was observed to increase from 0.04% of total SARS-CoV-2 spike–specific IgG after two doses to 19.27% after three doses.
Thus, the authors showed that mRNA technology is the culprit.
This explanation from a year ago shows why “immune tolerance” is harmful when an organism responds to a virus:
Mistakes Were Made (with mRNA)
mRNA technology has been around in scientific labs and startup companies for decades. Not one of its applications became an approved product before the Covid pandemic.
Somehow, science funders and health authorities rushed to adopt this failed technology to protect us from a disease that they coincidentally developed and funded.
We were told this technology was “safe and effective” based on rushed three-month trials. Later, we were told that “billions were vaccinated and no one died” – and we were forbidden to question the outcomes.
Then, surprises started.
Approximately a year after billions were vaccinated, mRNA-vaccinated people started getting infected and reinfected a lot more than the unvaccinated people! A study done on 50,000 health workers in Cleveland shows this:
The study discussed today proves that the IgG4 class switch (causing this increased rate of reinfections) did not occur merely due to the number of jabs received.
What mattered was what was injected: three mRNA injections caused a thousand times higher IgG4 levels than three Novavax injections.
Conflicts of Interest
The study, which we looked at today, was funded by Novavax. Hence, a standard dose of scepticism is warranted.
However, its findings confirm what we have discussed many times: the mRNA vaccines create a broken immune response, which fuelled the pandemic and made it worse rather than better.
I am not a shill for Novavax, and I would never take a Covid vaccine of any kind, including Novavax. The objective of my post, instead, is to highlight the insanity and irreversibility of recklessly priming billions of people with an unproven novel tolerance-inducing genetic treatment.
I wish they studied this effect before forcing billions of unwilling people to become subjects of a poorly considered planetary-scale science project.
This article was first published on Igor’s Substack page. Subscribe here.
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One aspect of military-inspired gain of function experiments is that, whilst they are creating dangerous new viruses, at the same time they create a “vaccine” in order to protect their own side.
Having created and (whether deliberately or accidentally) released Covid 19, they needed to test the efficacy of their “vaccines.” I strongly suspect that the reason some batches have been found to be considerably more dangerous than others is because they were trialling different concoctions.
“The objective of my post, instead, is to highlight the insanity and irreversibility of recklessly priming billions of people with an unproven novel tolerance-inducing genetic treatment.”
This statement contains an element of ‘cock-up theory’ and that is decidedly not what has occurred. If the so-called “vaccines” were proving to be iffy – and they damned well were – then their use should have been stopped PDQ but they weren’t. Why?
The intention has always been to jab as many people on this planet as possible so there must be a motive behind this. Given that the injections are maiming and killing those responsible for their dissemination must be aware that these were dangerous products and yet still they are being pushed.
The reality is that these poisonous products are not remotely connected to true therapeutics, they were manufactured to maim, sterilise and kill and that is what they are achieving.
The only experimentation, if there was any, was in the toxicity levels and that done as a precursor to the release of Billy’s Disesse X.
As I have posted many times the injections were brewed to a recipe and deliberately designed to maim and kill. There is no evidence indicating my position is faulty.
You are right the scam is the jabs not the engineered virus which could never be too deadly, otherwise it would kill and maim those who created it.
That is their dilemma, that in order to show up the non compliant it would also show up that the non compliant were healthier than the compliant.
I can understand they might have been testing different strengths of the toxic mix but surely if they were genuinely inquiring into its effects, they would monitor it more closely.
As it is, the stuff was systematically stabbed into anyone willing to roll up their sleeve, plus a few unfortunates who couldn’t object e.g young children or those with no agency. There was zero follow-up; only Yellow card or vaers which were completely ignored.
The stuff is junk and no doubt thrown together for nefarious purposes but I can’t credit that any kind of undercover testing was going on without monitoring the effects.
I cannot fathom how anyone can think that there is such a thing as a “covid vaccine”.
“mistakes were made”. The mistake was that too many of our fellow citizens sleepwalked their way to being injected with what seems to amount to a toxin.
Resisting the pressure and refusing the jab was a great decision and it’s looking better every day.
However, few will believe it, unless perhaps a TV drama is made.
When covid came on the scene I did a lot of researching on the internet and this video really opened my eyes to the jab and helped me decide not to take it.
https://thehighwire.com/videos/dels-football-analogy-goes-viral/