The journal Cell Host & Microbe recently published one of the more important papers of the Covid era: ‘Rethinking next-generation vaccines for coronaviruses, influenza viruses, and other respiratory viruses’. This elicited surprisingly little fanfare considering its authorship and contents. Firstly, the final author was Dr. Anthony Fauci, the recently retired Director of the United States National Institute of Allergies and Infectious Diseases (NIAID), normally a magnet for the media. Secondly, because Dr. Fauci and his co-authors provide evidence that much of what those in authority have told the public regarding Covid vaccines was contrary to what they knew to be true.
Kudos to Dr. Fauci for coming clean on the basics of viruses and immunology. If leading medical journals such as the New England Journal of Medicine or Lancet had employed editors with such knowledge three years ago, they might have contributed to public health rather than the gutting of society and global human rights. If those in authority had explained these truths and based their policies on them, things would also have been different. Likewise for the entire medical establishment. Much death, poverty and inequality might have been avoided. Trust may also have been maintained in the institutions within which they work.
The paper co-written by Dr. Fauci discusses the potential to develop coronavirus vaccines and vaccines for other fast-mutating respiratory viruses. It is best to step through the paper in three parts: reviewing the evidence provided by the authors, noting the residual dogma that persists despite being contrary to this evidence, and lastly considering the implications of the paper regarding the Covid public health response. Reading the original paper is recommended, as this article only highlights extracts.
Poor vaccine efficacy and the superiority of natural immunity
The review makes clear that vaccines against respiratory viruses such as influenza or coronaviruses (e.g. SARS-CoV-2 responsible for Covid) are highly unlikely to achieve the levels of effectiveness we expect from other vaccines. The authors note CDC data showing influenza vaccines, now pushed for all ages from six months upward, have an efficacy ranging from just 14% to a maximum of 60% since 2005 (extending back 17 years would have lowered this to 10%, with the average vaccine efficacy (VE) just below 40%). As Dr. Fauci notes: “Our best approved influenza vaccines would be inadequate for licensure for most other vaccine-preventable diseases.”
Indeed: “It is not surprising that none of the predominantly mucosal respiratory viruses have ever been effectively controlled by vaccines.”
The authors provide clear explanations for this lack of efficacy:
The vaccines for these two very different viruses have common characteristics: they elicit incomplete and short-lived protection against evolving virus variants that escape population immunity.
It is not just the high mutation rate that is a problem, but also the mode of infection:
They replicate predominantly in local mucosal tissue, without causing viremia, and do not significantly encounter the systemic immune system or the full force of adaptive immune responses, which take at least five to seven days to mature, usually well after the peak of viral replication and onward transmission to others.
As this honest appraisal notes, Covid vaccines were never expected to significantly reduce infection or transmission.
The authors explain what most infectious disease doctors and immunologists have known throughout the Covid outbreak: that circulating antibodies (IgG and IgM) play only a limited role in controlling infections such as Covid, whilst mucosal antibodies (IgA) in the lining of the upper respiratory tract, not stimulated by injected vaccines, play a far larger role:
The importance of mucosal secretory IgA (sIgA) in pathogen-specific responses against respiratory viral infections has long been appreciated for influenza viruses, RSV and more recently SARS-CoV-2.
The significance here is that systemic vaccines, as the authors note, do not elicit mucosal IgA production.
The efficacy against severe Covid that systemic vaccines do provide to some unexposed people within a certain window is explained by the observation: “IgA appears to be a better effector in the upper respiratory tract, whereas IgG is better in the lung.”
The early variants of SARS-CoV-2 were characterised by lung involvement. While the CDC showed that vaccination on top of natural immunity provides almost no added clinical benefit, the reduction in Covid mortality (as distinct from all-cause mortality) claimed for the vaccines between early potential immune suppression and later waning of efficacy has a reasonable immunological basis.
As NIH acknowledged, T-cells are also a primary defence against coronaviruses, with cross-immunity against SARS-CoV-2 seen in many people not previously infected. Fauci et al. make the interesting observation that T-cell correlates for immunity are found after influenza infection, but not after influenza vaccination. This suggests a further mechanism to explain poorer efficacy of vaccines compared to natural infection, even against early SARS-CoV-2 variants.
In summary, both the coronavirus and influenza vaccines are poor:
The vaccines for these two very different viruses have common characteristics: they elicit incomplete and short-lived protection against evolving virus variants that escape population immunity.
Clear, and succinctly put.
Struggling with the dogma
The real value of the paper is in the way it contrasts Covid dogma against evidence. The authors start by noting that as many as five million people normally die globally every year from respiratory viruses. A comparison with the World Health Organisation’s 6.8 million Covid deaths recorded over three years would have provided useful context (Note: is it important to distinguish deaths from Covid from total deaths from the pandemic that include those from Covid and lockdown impact.) However, such an acknowledgement would have fit poorly with their following statement that: “SARS-CoV-2 has killed more than one million people in the United States.”
This is, of course, false. It is based on deaths after a recent positive PCR result, with CNN’s Covid analyst now admitting the exaggerations involved. More strangely, the authors claim: “The rapid development and deployment of SARS-CoV-2 vaccines has saved innumerable lives and helped to achieve early partial pandemic control.”
That the vaccines appear to have saved too many lives for the authors to contemplate is surprising. Dr. Fauci felt able to contemplate numbers of deaths during the first year of the Covid outbreak when the virus hit a population said to have no prior immunity. Recorded mortality was similar in the second year, after mass vaccination was imposed, despite severe disease being heavily concentrated in a relatively small, well-defined elderly minority who were prioritised by the vaccination programme. It is therefore more plausible that the vaccines averted relatively few deaths. Such a lack of impact is fully in line with the expectations of the authors noted above.
Achieving “early partial epidemic control” is just strange for authors who have noted that the IgG response does not really kick in until after the peak of viremia and transmission. Putting dogma up against evidence is really hard when you have staked your reputation on the dogma, so the struggle apparent here is understandable.
In recognition of the impact of reality on the Covid vaccine programme, we can accept the rather vague acknowledgement that despite vaccination: “Significant numbers of fatalities [amongst the vaccinated] still occur.”
As the authors recognise: “Attempting to control mucosal respiratory viruses with systemically administered non-replicating vaccines has thus far been largely unsuccessful.”
The importance of this paper
The authors of this paper are not developing new hypotheses to explain why Covid vaccine performance was disappointing. They are simply re-stating previous knowledge. Predictions of high and sustained vaccine efficacy, and vaccination paving the ‘way out of the pandemic’, were not expected to come true. These claims were a ploy to encourage adherence to a plan that would dramatically enrich certain corporate and public health figures. People with reasonable knowledge of the subject knew the rhetoric to be incorrect, though relatively few said so. The rest, presumably, were fooled.
Fauci and co-authors therefore make an important contribution to the Covid narrative, underlining the deception of the past two years. Claims that this deception promoted an overall good – that there was a ‘global pandemic’ and compliance with mass vaccination would be for the population’s benefit – are refuted by Fauci et al.’s evidence. Mass vaccination, while very successful financially for a small but influential minority, was never expected to work.
Natural immunity was always going to be more effective than vaccines, and statements to the contrary such as the John Snow Memorandum promoted by the Lancet contradicted expert understanding and common sense. Denigration of those pointing out the relative superiority of natural immunity was slander. When the last author of this paper stated publicly that COVID-19 vaccines work much better than natural immunity to protect you against coronavirus, he knew that was highly unlikely to be true.
The public health community misled the public to promote injections with a new class of pharmaceutical. They had no long-term safety data, the vaccines targeted a virus they knew posed little harm to the vast majority of those to whom they were speaking, while many already had more effective natural immunity. The long-term outcomes of this deception are yet to play themselves out, and will include a loss of trust in public health and the practice of medicine. This is justified, and can be argued to be a good thing. How each person reacts to confirmation that they have been fooled by those who promoted this narrative is an individual choice. The most foolish reaction would be to pretend that the deception did not occur.
Dr. David Bell is a clinical and public health physician with a PhD in population health and background in internal medicine, modelling and epidemiology of infectious disease. Previously, he was Director of the Global Health Technologies at Intellectual Ventures Global Good Fund in the USA, Programme Head for Malaria and Acute Febrile Disease at FIND in Geneva, and coordinating malaria diagnostics strategy with the World Health Organisation. He is a member of the Executive Committee of PANDA. This article was first published by the Brownstone Institute.
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Dr Fraudci, another Dr Baffled and Dr Corrupt.
His bank account is happily immune to investigation. It collected kickbacks, graft and backhanders from his buddies in Pharma, safely and effectively.
Prison is too good for this evil, egotistical Pope of Pharma Pfaith and Pfraud.
And still our MSM will not touch this story. They must still be being paid off.
Here’s my take:
Whether the vaccines worked was never the issue.
They were hastily marketed to be used as a vehicle to introduce the well established digital ID system trialled in China that would conveniently also include vaccine status.
Those of us who fought hard to stave off digital vaccine ID now have to fight the two pronged assault on our inalienable liberties of digital ID and programmable central bank digital currency.
Once introduced, your freedoms become the gift of the state.
This is what happened:
Boom!
I think we need to start calling them 15 minute ghettos or ghetto cities – they won’t like that: cities sound benign whereas ghettos implies prison-like.
Good point.
15 minute ghettos has unfortunate echoes of the Warsaw Ghetto and might focus a few minds.
What happened to the evil little gnome’s ”highly effective” mantra then?? And talking of nasty, unappetizing things that are bad for your health…over to the appealing topic of lab-grown meat, and did you know how it’s actually grown?
”The main problem of growing an endless “lab meat” supply is that normal tissue cells cannot endlessly replicate (see above). There is a limit on how many times they will divide.
Vaccine manufacturers already use such immortalized tumor cells to make some Covid vaccines and other vaccines.
Thus, “lab meat” and “cell line” suppliers grow meat from tumor cells that are “immortalized”; in other words, their cells can endlessly replicate. This is why cancers never stop growing, after all!” I’ll have a side order of deep-fried Crunchy Crickets please!
https://igorchudov.substack.com/p/lab-grown-meat-is-made-of-cancer
“That the vaccines appear to have saved too many lives for the authors to contemplate…”
Thank you for that sentence, a well-deserved smack for their ridiculous claims of ‘saving millions of lives’, with zero evidence. $cience in 2022 = repeat the lie, repeat the lie, repeat the lie, until it becomes “The Science”.
It’s been extraordinary to see how so many so-called experts and highly educated people could never be bothered to (be willing to) see that simple fact – if the claim were true, we should have seen fewer deaths in 2021 and 2022, not the same number of excess deaths or indeed more, than in 2020. There’s The Science, and there’s what you can see with your own eyes.
When I now read the inevitable “the vaccines are responsible for saving millions of lives throughout the world” in any paper pointing out yet another “side effect” of the poison, I get the feeling those writing it are now trolling. They know it’s bunk, they know they have to add that ludicrous sentence or otherwise the paper won’t get published, but the phrase always stands in such sharp contrast to what the rest of the paper says, that it’s pretty much a running joke now, right up there with “safe and effective”.
“Fauci and co-authors therefore make an important contribution to the Covid narrative, underlining the deception of the past two years.”
What a wonderfully underplayed sentence and sneaking in below the wire.
“Straight to the heart and then twisted – get in there.”
Love it.
Fauci doesn’t exactly come clean.
He seems to present evidence that the jabs don’t really do much. But then he still makes the assertion that they do.
The author then infers that Fauci must have known this all along because the reasons he gives for the lack of efficacy of COVID jabs is the same reasons all other respiratory jabs don’t work very well. And he presents no evidence that would have made him suspect otherwise.
So damn you for getting my hopes up that the man had admitted his fraud. :-). Nope, these people continue to plough on with their global bio-security take over.
I absolutely love the term “residual dogma” and I intend to use it particularly with the over educated, professional classes.
They like to see themselves as rational and scientifically minded and tend to be attracted to jargon.
“Residual dogma” makes a simple concept – being stubborn in the face of evidence – into something more intellectual and complicated, which these people love.
I think this jargon has a good chance of sticking to the rest of the jargon in their cluttered minds like fluff sticking to a bigger ball of fluff.
The International Criminal Court at The Hague (not Bliar’s latest sock puppet) ought to go after Fauci relentlessly, along with each and every one of the signatories to the infamous “conspiracy” letter to The Lancet. They should be made to testify to what they knew (or who put them up to signing) about GoF research that created the virus.
Unfortunately the Court is run by and for the dominant Powers, so zero chance of that happening.
In the real world, Prof. Bhakdi is facing trial for saying just this, esp. warning of the mucosal flaw, and Clemens Arvay, the first person in the German speaking world delving deeper into the gene therapies and their trials and someone who thereby really saved millions of peoples health, has just committed suicide, not least due to the hate speech he had to face from so called fact checkers, tabloids and Wikipedia hacks.
RIP.
I hadn’t heard of Clemens Arvay, but looked him up. Sounds like an interesting person, so very sad news. I did however find a funny quote in Wikipedia under his bio – “According to Robert Koch Institute (RKI), all COVID-19 vaccines approved in the European Union are safe, effective and, overall, have a good risk-benefit profile according to the current state of science (1 April 2021).[43]“
Trouble is mistah you have twenty million deaths on your hands already soon to rise to thrity million.There aint no scientific paper way out of it. When the truth hits the mainstream I guarantee you that the masses will be baying like wild dogs on a scale beyond our comprehension. All of this chatter will count for nothing in a climate of such rage. Fauci will curse the day that he was born. A sellout is a sellout.
I wish I could summon up the energy to feel sorry for you but with a death toll in the tens of millions I wish you good luck because you are going to need it.
The American Bio-Defence Military had a shiny new toy to play with: mRNA, which they intended / intend to use as a platform technology for many purposes.
They needed to test it on a very large group of human guinea pigs. So they co-opted Big Pharma; Global Health Bureaucrats; Big Tech and Mainstream Media.
And the rest is now history. Hundreds of thousands killed by the jabs; millions whose health has been damaged for life.
But the American Bio-Defence Military have the data they needed so the likes of Fauci have been retired and are now allowed to take steps back from the propaganda they endorsed.
I’m tired and messing about, how about he he is a flat faced liar, bullied people in to getting something that was not fit for purpose, actually toxic, then anyone that resisted him, professionally and personally dismantled them, continued doing this, and all the time being protected by his wife who was meant to be overseeing him he should be getting prosecuted for being complicit in the very least manslaughter, or am I being too harsh? I don’t think so, all the people accountable for any involvement in the crimes carried out be brought to justice, , which includes most of the government!!
There is one especially chilling sentence in that paper that really tells us where Fauci and his friends are coming from.
“Attempting to control mucosal respiratory viruses with systemically administered non-replicating vaccines has thus far been largely unsuccessful.”
NON-REPLICATING. Basically, they want to go beyond mRNA vaccines to a replicating vaccine. The mRNA vaccines tell your cells to make the COVID spike protein. A replicating vaccine would tell your cells to make copies of itself. It would, in other words, be an artificial virus.
This is where Fauci and his friends are going, and that is why the paper is titled “Rethinking next generation vaccines…”
Far from coming clean, he is promoting the next step in their insanity.
You cannot ignore the whole covid theatre was hugely profitable to politicians & their friends, public health officials, big business and the vaccine oligarchs. It has been reported Bill Gates net worth increased by 80 billion. Other causes aside, this was enough to drive this covid debacle.