27 March 2021  /  Updated 17 July 2021
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This will speed up herd immunity

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Splatt
Posts: 1609
(@splatt)
Joined: 1 year ago

Just wondering if anyone here is worried about, or even aware of the disaster of SARS1/Mers vaccines, and the reasons why neither of those ever materialised?!

Same reason most vaccines never materialise - the disease goes away and/or funding dries up.

Ebola took ages to come forward due to the lack of people catching Ebola for trials for example.
I thought we sceptics were better informed than to place hope in a potentially dangerous experiment that's intended to neither prevent contagion or transmission.

Its undergone the same tests as any other. And many vaccines do not prevent infection or transmission. Its not unusual.
Can't say I'm looking forward to the days when all the vaxxed get extremely sick come next coronavirus season, and having it labelled a 3rd/4th/5th wave that necessitates more lockdowns.

Absolutely nothing to suggest it will.
Will that happen? I don't know, and nor do the experts.

They have a far better idea given the studies done. We know what causes these things and we also know how to mitigate.
Remembe people who got the flu shot several years running were 3x more sick during swine flu than non-vaxxed. Search Antibody dependent enhancement.
https://www.bmj.com/content/368/bmj.m626/rr

ADE is rare and fairly well understood. We know for the 2 mRNA vaccines the chances of that are minute due to the very specific antibodies generated (its a risk when similar but less effective are produced). mRNA has potential to eliminate that risk entirely if done properly.

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fon
Posts: 1356
 fon
Topic starter
(@fon)
Joined: 12 months ago

And many vaccines do not prevent infection or transmission. Its not unusual.

That would be a disaster. It is very important that a vaccine make a person less likely to transmit SARS-CoV-2 to others. AstraZeneca and Oxford have said vaccinated people had fewer asymptomatic infections, which suggests they were less likely to transmit SARS-CoV-2 to others.

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fon
Posts: 1356
 fon
Topic starter
(@fon)
Joined: 12 months ago

ADE is rare and fairly well understood. We know for the 2 mRNA vaccines the chances of that are minute due to the very specific antibodies generated (its a risk when similar but less effective are produced). mRNA has potential to eliminate that risk entirely if done properly.

That is good to know, it is also good that Astra Zeneca Oxford specifically mention results which show that vaccinated people are less likely to transmit the virus.

https://www.ox.ac.uk/news/2020-11-23-oxford-university-breakthrough-global-covid-19-vaccine

  • Phase 3 interim analysis including 131 Covid-19 cases indicates that the vaccine is 70.4% effective when combining data from two dosing regimens

  • In the two different dose regimens vaccine efficacy was 90% in one and 62% in the other

  • Higher efficacy regimen used a halved first dose and standard second dose

  • Early indication that vaccine could reduce virus transmission from an observed reduction in asymptomatic infections

  • There were no hospitalised or severe cases in anyone who received the vaccine

  • large safety database from over 24,000 volunteers from clinical trials in the UK, Brazil and South Africa, with follow up since April

  • Crucially, vaccine can be easily administered in existing healthcare systems, stored at ‘fridge temperature’ (2-8 °C) and distributed using existing logistics

  • Large scale manufacturing ongoing in over 10 countries to support equitable global access
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    miahoneybee
    Posts: 1541
    (@miahoneybee)
    Joined: 1 year ago

    Anyone would think you had shares in the vaccine companies. We all know you want the vaccine is it necessary to mention it in every post..

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    Splatt
    Posts: 1609
    (@splatt)
    Joined: 1 year ago
  • Early indication that vaccine could reduce virus transmission from an observed reduction in asymptomatic infections
  • Except what they say isn't what you claim.

    Firstly "could" - the data isn't sufficient to be analysed.
    Also its not measuring transmission - its measuring a perceived reduction in asymptomatics. Thats 2 levels removed from what you claim.

    (We also know the 1:1 Oxford is only 61% efficacy as well)

    You're the only one misreading and claiming things the vaccine makers themselves do not claim.
    We have no data. We still dont. We wont have for a long time to come.

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